For nearly two decades, Resident Evil 4 has remained a gold standard in survival horror and action gaming. Originally released for the Nintendo GameCube in 2005, Capcom’s masterpiece has been ported to almost every conceivable platform—from the PlayStation 2 to the iPhone, and even the Zeebo. Yet, one question haunts the forums and ROM sites more persistently than any Ganado: Can you play Resident Evil 4 on the PlayStation Portable (PSP) using an ISO or CSO file?